Why We're Here

Novel, Life-Improving Options for Patients with Oncogene Amplified Cancers


Our Mission

Be the foremost biopharma company interrogating extrachromosomal DNA (ecDNA) biology to deliver transformative therapies to patients with intractable oncogene amplified cancers.


Our Vision

A world in which patients with ecDNA-driven cancers have access to powerful anti-cancer therapies that improve and extend their lives.

Patients with Oncogene Amplification

Boundless Bio’s strategy is to leverage our unique expertise in ecDNA biology and its role in oncogene amplified cancer to pioneer the discovery, development, and commercialization of transformative therapies that improve and extend the lives of patients with intractable oncogene amplified cancers.

Boundless Bio’s Core Values


We not only want to, but believe that we can, achieve unprecedented things--it is our base case assumption that we will, employing passion, innovation, and urgency to propel us.


We are devoted and accountable to each other, our products, and our patients. We take pride in seeing a task through to completion, on time, giving 100% of ourselves along the way. We value those who relentlessly find a way to obtain answers and propose solutions, without accepting no as an answer.


Because we are in the business of generating novel molecules to be dosed to patients, extreme dedication to quality—of product and character—pervades everything we do. No product, task, or interaction that we engage in receives anything less than our utmost care and integrity.


As a cell is a complex organism that relies on different components functioning in an integrated manner to thrive, so too is a vibrant biotechnology company. All disciplines are interdependent and must operate in lockstep teamwork for our company organism to succeed.


All data, facts, and opinions must be revealed and communicated to enable fully informed decision-making under otherwise murky circumstances. We all have an obligation to speak up, to listen, and to ask questions. All inputs are considered.


We care deeply about our fellow human beings, including our colleagues, business partners, and customers (patients and physicians). We welcome diversity, we seek to understand each other, and we embrace our differences, without judgment.

We are pioneering a new approach in precision oncology

“Boundless Bio is pioneering a new approach to treating cancer that is distinct from how we’ve attempted to treat cancer in the past. Historically, the field has treated the protein products of activated oncogenes, for instance receptor tyrosine kinases. At Boundless Bio, we’re treating the underlying process by which overexpressed oncogenes arise and perpetuate in the first place. Specifically, ecDNA, which are a key driver of oncogene amplifications”

Zachary Hornby

Chief Executive Officer


Who We Are

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